Simultaneous measurement of major metabolites of dolasetron mesilate in human urine using solid phase extraction and HPLC
Summary
Type: HPLC Application #: 103990
Detection: UV, 280 nm Conditions: temperature: 30 °C
eluent A: acetonitrile / 0.05 M ammonium acetate (10 : 90, v/v)
eluent B: acetonitrile / 0.05 M ammonium acetate (60 : 40, v/v); pH in both cases adjusted to 4.7 by dropwise addit Authors: Sanwald P Source: J Chromatogr B 661 (1994) 101 - 107
Details
Legend: Fig. 1: Chromatographic separation of III (13.4), IV (13.9), II (18.7) and V
(I.S.) (20.9 min) extracted from human urine.
(a) Blank urine
(b) urine spiked with standards (2000 pmol/ml)
(x) unid